A 25-year-old woman came with abdominal pain and distension since five days. She was known to have Von Willebrand disease. Her last menstrual period was one month ago. Urine pregnancy test was negative, Beta HCG levels were within normal range.
Transabdominal ultrasonography shows gross ascites with coarse echoes. Transvaginal ultrasonography shows an ill-defined, heterogeneously hyperechoic avascular lesion in the pelvis, approximately 60-70 mL in volume situated anterior to the uterus. The left adnexa shows two cystic lesions. The larger cyst shows peripheral rim like calcifications and heterogeneously hyperechoic content and measures 4.1 x 4 x 4.4 cm. The left ovary is not seen separately.
von Willebrand disease is named after Erik von Willebrand, a Finnish physician who studied a family with a bleeding disorder. He first described the condition in 1926 and distinguished it from haemophilia.